研究の成果

掲載論文

 

■ Cause-specific mortality in the general population with transient dipstick-proteinuria
Kei Nagai, Kunihiro Yamagata, Kunitoshi Iseki, Toshiki Moriyama, Kazuhiko Tsuruya, Shouichi Fujimoto, Ichiei Narita, Tsuneo Konta, Masahide Kondo, Masato Kasahara, Yugo Shibagaki, Koichi Asahi, Tsuyoshi Watanabe Research Article | published 02 Oct 2019 PLOS ON

https://doi.org/10.1371/journal.pone.0223005

 

■ Higher medical costs for CKD patients with a rapid decline in eGFR: A cohort study from the Japanese general population
Kei Nagai, Chiho Iseki, Kunitoshi Iseki, Masahide Kondo, Koichi Asahi, Chie Saito, Ryoya Tsunoda, Reiko Okubo, Kunihiro Yamagata Research Article | published 17 May 2019 PLOS ONE

https://doi.org/10.1371/journal.pone.0216432

 

■ Antihypertensive treatment and risk of cardiovascular mortality in patients with chronic kidney disease diagnosed based on the presence of proteinuria and renal function
A large longitudinal study in Japan Kei Nagai, Kunihiro Yamagata, Kunitoshi Iseki, Toshiki Moriyama, Kazuhiko Tsuruya, Shouichi Fujimoto, Ichiei Narita, Tsuneo Konta, Masahide Kondo, Masato Kasahara, Yugo Shibagaki, Koichi Asahi, Tsuyoshi Watanabe Research Article | published 04 Dec 2019 PLOS ONE

https://doi.org/10.1371/journal.pone.0225812

 

■ Cause-specific mortality in the general population with transient dipstick-proteinuria.
Nagai K, Yamagata K, Iseki K, Moriyama T, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. PLoS One. 2019 Oct 2; 14: e0223005.

 

■ A prediction model with lifestyle in addition to previously known risk factors improves its predictive ability for cardiovascular death.
Nishimoto M, Tagawa M, Matsui M, Eriguchi M, Samejima KI, Iseki K, Iseki C, Asahi K, Yamagata K, Konta T, Fujimoto S, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Watanabe T, Tsuruya K. Sci Rep. 2019 Sep 10; 9: 12953.

 

■ Lower diastolic blood pressure was associated with higher incidence of chronic kidney disease in the general population only in those using antihypertensive medications.
Uchida D , Kido R, Kawarazaki H, Murasawa M, Ando A, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Konta T, Narita I, Kondo M, Kasahara M, Asahi K, Watanabe T, Shibagaki Y. Kidney Blood Press Res. 2019 Sep 5:1-11.

 

■ Fast eating is a strong risk factor for new-onset diabetes among the Japanese general population.
Kudo A, Asahi K, Satoh H, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. Sci Rep. 2019 Jun 3; 9: 8210.

 

■ Higher medical costs for CKD patients with a rapid decline in eGFR: A cohort study from the Japanese general population.
Nagai K, Iseki C, Iseki K, Kondo M, Asahi K, Saito C, Tsunoda R, Okubo R, Yamagata K.. PLoS One. 2019 May 17;14(5): e0216432.

 

■ New risk prediction model of coronary heart disease in participants with and without diabetes: Assessments of the Framingham risk and Suita scores in 3-year longitudinal database in a Japanese population.
Hirai H, Asahi K, Yamaguchi S, Mori H, Satoh H, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. Sci Rep 2019; 9: 2813. doi: 10.1038/s41598-019-39049-w.

 

■ Association between Prescription and Control Status of Dyslipidemia and Hypertension among Japanese Patients with Diabetes.
Sakamoto M, Edo N, Takahashi S, Okamura E, Uno K, Morita K, Ishikawa T, Asahi K, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kimura K, Ohashi Y, Watanabe T, Tsukamoto K. J Atheroscler Thromb. 2019; 26: 805-820.

 

■ Effect of Hypertension on Aortic Artery Disease-Related Mortality - 3.8-Year Nationwide Community-Based Prospective Cohort Study.
Otaki Y, Watanabe T, Konta T, Watanabe M, Fujimoto S, Sato Y, Asahi K, Yamagata K, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Circ J. 2018; 82: 2776-2782.

 

■ Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population.
Ogata E, Asahi K, Yamaguchi S, Iseki K, Sato H, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. Sci Rep. 2018 Sep 17; 8:13927.

 

■ Dipstick proteinuria and all-cause mortality among the general population.
Iseki K, Konta T, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Iseki C, Watanabe T. Clin Exp Nephrol. 2018; 22:1331-1340.

 

■ Alcohol consumption and incidence of proteinuria: a retrospective cohort study.
Kimura Y, Yamamoto R, Shinzawa M, Isaka Y, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Moriyama T, Watanabe T. Clin Exp Nephrol. 2018 ;22:1133-1142.

 

■ Glucosuria and all-cause mortality among general screening participants.
Iseki K, Konta T, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Iseki C, Watanabe T. Clin Exp Nephrol 2018; 22: 850-859.

 

■ Anemia as a risk factor for all-cause mortality: obscure synergic effect of chronic kidney disease.
Sato Y, Fujimoto S, Konta T, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. Clin Exp Nephrol 2018; 22: 388-394.

 

■ Association between renal function and cardiovascular and all-cause mortality in the community-based elderly population: results from the Specific Health Check and Guidance Program in Japan.
Kon S, Konta T, Ichikawa K, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Clin Exp Nephrol 2018; 22: 346-352

 

■ Association of dipstick hematuria with all-cause mortality in the general population: results from the Specific Health Check and Guidance program in Japan.
Iseki K, Konta T, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Iseki C, Watanabe T. Nephrol Dial Transplant 2018; 33: 825-833.

 

■ Mortality risk among screened subjects of the specific health check and guidance program in Japan 2008-2012. “Design of the comprehensive health care system for chronic kidney disease (CKD) based on the individual risk assessment by Specific Health Check”.
Iseki K, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Konta T, Kasahara M, Shibagaki Y, Yoshida H, Moriyama T, Kondo M, Iseki C, Watanabe T. Clin Exp Nephrol 2017; 21: 978-985.

 

■ Body shape index: sex-specific differences in predictive power for all-cause mortality in the Japanese population.
Sato Y, Fujimoto S, Konta T, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. PLoS One 2017; 12: e0177779.

 

■ Association of hypertriglyceridemia with the incidence and progression of chronic kidney disease and modification of the association by daily alcohol consumption.
Tsuruya K, Yoshida H, Nagata M, Kitazono T, Iseki K, Iseki C, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kimura K, Kondo M, Asahi K, Watanabe T. J Ren Nutr 2017; 27: 381-394

 

■ The association of alcohol and smoking with CKD in a Japanese nationwide cross-sectional survey.
Matsumoto A, Nagasawa Y, Yamamoto R, Shinzawa M, Hasuike Y, Kuragano T, Isaka Y, Nakanishi T, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Moriyama T, Watanabe T. Hypertens Res 2017; 40: 771-778.

 

■ Association between overall lifestyle changes and incidence of proteinuria: a population-based, cohort study.
Wakasugi M, Kazama JJ, Narita I, Iseki K, Fujimoto S, Moriyama T, Yamagata K, Konta T, Tsuruya K, Asahi K, Kondo M, Kurahashi I, Ohashi Y, Kimura K, Watanabe T: Intern Med 2017; 56: 1475-1484.

 

■ Associations between serum uric acid levels and the incidence of nonfatal stroke: a nationwide community-based cohort study.
Kamei K, Konta T, Hirayama A, Ichikawa K, Kubota I, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T: Clin Exp Nephrol 2017; 21: 497-503.

 

■ Control status of atherosclerotic cardiovascular risk factors among Japanese high-risk suubjects: Analyses of a Japanese Health Check Database from 2008 through 2011.
Hasegawa K, Tsukamoto K, Kunimi M, Asahi K, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kimura K, Kurahashi I, Ohashi Y, Watanabe T. J Atheroscler Thromb 2016; 23: 991-1003.

 

■ Body mass index modifies an association between self-reported regular exercise and proteinuria.
Nagasawa Y, Yamamoto R, Shinzawa M, Hasuike Y, Kuragano T, Isaka Y, Nakanishi T, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Moriyama T, Watanabe T. J Atheroscler Thromb. 2016; 23: 402-412.

 

■ Long-term blood pressure variability, new-onset diabetes mellitus, and new-onset chronic kidney disease in the Japanese general population.
Yano Y, Fujimoto S, Kramer H, Sato Y, Konta T, Iseki K, Iseki C, MoriyamaT, Yamagata K, Tsuruya K, Narita I, Kondo M, Kimura K, Asahi K, Kurahashi I, Ohashi Y, Watanabe T: Hypertension 2015; 66: 30-36.

 

■ Impact of the triglycerides to high-density lipoprotein cholesterol ratio on the incidence and progression of chronic kidney disease: a longitudinal study in a large Japanese population.
Tsuruya K, Yoshida H, Nagata M, Kitazono T, Iseki K, Iseki C, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kimura K, Kondo M, Asahi K, Kurahashi I, Ohashi Y, Watanabe T: Am J Kid Dis 2015; 66: 972-983.

 

■ Blood Pressure, Proteinuria, and Renal Function Decline: Associations in a Large Community-based Population.
Hirayama A, Konta T, Kamei K, Suzuki K, Ichikawa K, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Kimura K, Narita I, Kondo M, Asahi K, Kurahashi I, Ohashi Y, Watanabe T: Am J Hypertens 2015; 28: 1150-1156.

 

■ Significance of estimated glomerular filtration rate in predictingbrain or heart attacks in obese and non-obese populations.
Sato Y, Fujimoto S, Konta T, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Kimura K, Narita I, Kondo M, Asahi K, Kurahashi I, Ohashi Y, Watanabe T: Clin Exp Nephrol 2015; 19: 790-796.

■ Association between hypouricemia and reduced kidney function: a cross-sectional population-based study in Japan.
Wakasugi M, Kazama JJ, Narita I, Konta T, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Asahi K, Kimura K, Kondo M, Kurahashi I, Ohashi Y, Watanabe T: Am J Nephrol 2015; 41: 138-146.

 

■ Underestimating chronic kidney disease by urine dipstick without serum creatinine as a screening tool in the general Japanese population.
Uchida D, Kawarazaki H, Shibagaki Y, Yasuda T, Tominaga N, Watanabe T, Asahi K, Iseki K, Iseki C, Tsuruya K, Yamagata K, Moriyama T, Narita I, Fujimoto S, Konta T, Kondo M, Kasahara M, Kimura K. Clin Exp Nephrol. 2015; 19: 474-80.

 

■ Comparison of predictive value for first cardiovascular event between Japanese GFR equation and coefficient-modified CKD-EPI equation.
Terawaki H, Nakayama M, Asahi K, Kakamu T, Hayakawa T, Iseki K, Kimura K, Moriyama T, Yamagata K, Narita I, Fujimoto S, Tsuruya K, Konta T, Kondo M, Kurahashi I, Ohashi Y, Fukushima T, Watanabe T. Clin Exp Nephrol. 2015; 19: 387-94.